Long-range correlations in the mechanics of small DNA circles under topological stress revealed by multi-scale simulation

It is well established that gene regulation can be achieved through activator and repressor proteins that bind to DNA and switch particular genes on or off, and that complex metabolic networks deter- mine the levels of transcription of a given gene at a given time. Using three complementary computa-...

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Bibliographic Details
Main Authors: Sutthibutpong, Thana, Matek, Matek, Benham, Craig, Slade, Gabriel G., Noy, Agnes, Laughton, Charles A., Doye, Jonathan P.K., Louis, Ard A., Harris, Sarah A.
Format: Article
Language:English
Published: Oxford University Press 2016
Online Access:http://eprints.nottingham.ac.uk/42944/
http://eprints.nottingham.ac.uk/42944/
http://eprints.nottingham.ac.uk/42944/
http://eprints.nottingham.ac.uk/42944/7/gkw815.pdf