Immunostaining for DNA modifications: computational analysis of confocal images

For several decades, 5-methylcytosine (5mC) has been thought to be the only DNA modification with a functional significance in metazoans. The discovery of enzymatic oxidation of 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) as well as detection of N6-met...

Full description

Bibliographic Details
Main Authors: Ramsawhook, Ashley, Lewis, Lara C., Eleftheriou, Maria, Abakir, Abdulkadir, Durczak, Paulina M., Markus, Robert, Rajini, Seema, Hannan, Nicholas R.F., Coyle, Beth, Ruzov, Alexey
Format: Article
Language:English
Published: Journal of Visualized Experiments 2017
Online Access:http://eprints.nottingham.ac.uk/42816/
http://eprints.nottingham.ac.uk/42816/
http://eprints.nottingham.ac.uk/42816/
http://eprints.nottingham.ac.uk/42816/8/Immunostaining.pdf