Reconstruction and simulation of neocortical microcircuitry

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of juvenile rat. The reconstruction uses cellular and synaptic organizing principles to algorithmically reconstruct detailed anatomy and physiology from sparse experimental data. An objective anatomical met...

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Main Authors: Markram, Henry, Muller, Eilif, Ramaswamy, Srikanth, Reimann, Michael W., Abdellah, Marwan, Sanchez, Carlos Aguado, Ailamaki, Anastasia, Alonso-Nanclares, Lidia, Antille, Nicolas, Arsever, Selim, Kahou, Guy Antoine Atenekeng, Berger, Thomas K., Bilgili, Ahmet, Buncic, Nenad, Chalimourda, Athanassia, Chindemi, Giuseppe, Courcol, Jean-Denis, Delalondre, Fabien, Delattre, Vincent, Druckmann, Shaul, Dumusc, Raphael, Dynes, James, Eilemann, Stefan, Gal, Eyal, Gevaert, Michael Emiel, Ghobril, Jean-Pierre, Gidon, Albert, Graham, Joe W., Gupta, Anirudh, Haenel, Valentin, Hay, Etay, Heinis, Thomas, Hernando, Juan B., Hines, Michael, Kanari, Lida, Keller, Daniel, Kenyon, John, Khazen, Georges, Kim, Yihwa, King, James G., Kisvarday, Zoltan, Kumbhar, Pramod, Lasserre, Sébastien, Le Bé, Jean-Vincent, Magalhães, Bruno R.C., Merchán-Pérez, Angel, Meystre, Julie, Morrice, Benjamin Roy, Muller, Jeffrey, Muñoz-Céspedes, Alberto, Muralidhar, Shruti, Muthurasa, Keerthan, Nachbaur, Daniel, Newton, Taylor H., Nolte, Max, Ovcharenko, Aleksandr, Palacios, Juan, Pastor, Luis, Perin, Rodrigo, Ranjan, Rajnish, Riachi, Imad, Rodríguez, José-Rodrigo, Riquelme, Juan Luis, Rössert, Christian, Sfyrakis, Konstantinos, Shi, Ying, Shillcock, Julian C., Silberberg, Gilad, Silva, Ricardo, Tauheed, Farhan, Telefont, Martin, Toledo-Rodriguez, Maria, Tränkler, Thomas, Van Geit, Werner, Díaz, Jafet Villafranca, Walker, Richard, Wang, Yun, Zaninetta, Stefano M., DeFelipe, Javier, Hill, Sean L., Segev, Idan, Schürmann, Felix
Format: Article
Language:English
Published: Elsevier 2015
Online Access:http://eprints.nottingham.ac.uk/42775/
http://eprints.nottingham.ac.uk/42775/
http://eprints.nottingham.ac.uk/42775/
http://eprints.nottingham.ac.uk/42775/1/1-s2.0-S0092867415011915-main.pdf