Polygenic risk of psychosis and ventral striatal activation during reward processing in healthy adolescents

Importance: Psychotic disorders are characterized by attenuated activity in the brain’s valuation system in key reward processing areas, such as the ventral striatum (VS), as measured with functional magnetic resonance imaging. Objective: To examine whether common risk variants for psychosis are as...

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Main Authors: Lancaster, Thomas M., Linden, David E., Tansey, Katherine E., Banaschewski, Tobias, Bokde, Arun L.W., Bromberg, Uli, Büchel, Christian, Cattrell, Anna, Conrod, Patricia J., Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny A., Heinz, Andreas, Ittermann, Bernd, Martinot, Jean-Luc, Paillère Martinot, Marie-Laure, Artiges, Eric, Lemaitre, Herve, Nees, Frauke, Orfanos, Dimitri Papadopoulos, Paus, Tomáš, Poustka, Luise, Smolka, Michael N., Vetter, Nora C., Jurk, Sarah, Mennigen, Eva, Walter, Henrik, Whelan, Robert, Schumann, Gunter
Format: Article
Language:English
Published: American Medical Association 2016
Online Access:http://eprints.nottingham.ac.uk/39607/
http://eprints.nottingham.ac.uk/39607/
http://eprints.nottingham.ac.uk/39607/
http://eprints.nottingham.ac.uk/39607/1/yoi160037.pdf