One-pot ligation-oxidative deselenization at selenocysteine and selenocystine
The use of native chemical ligation at selenocysteine (Sec) with peptide thioesters and additive-free selenocystine ligation with peptides bearing phenyl selenoesters, in concert with one-pot oxidative deselenization chemistry, is described. These approaches provide a simple and rapid method for acc...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017
|
| Online Access: | http://eprints.nottingham.ac.uk/39311/ http://eprints.nottingham.ac.uk/39311/ http://eprints.nottingham.ac.uk/39311/ http://eprints.nottingham.ac.uk/39311/3/One-Pot%20Ligation-Oxidative%20Deselenization%20at%20Selenocysteine%20and%20Selenocystine_Chem_Eur_J_MITCHELL.pdf |