Systemic in vivo delivery of siRNA to tumours using combination of polyethyleneimine and transferrin–polyethyleneimine conjugates

Materials for delivery of oligonucleotides need to be simple to produce yet effective in vivo to be considered for clinical applications. Formulations of biomaterials based on combinations of existing demonstrated polymeric gene carriers with targeted derivatives are potential candidates for rapid t...

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Bibliographic Details
Main Authors: Grabowska, Anna M., Kircheis, Ralf, Kumari, Rajendra, Clarke, Philip, McKenzie, Andrew, Hughes, Jaime, Mayne, Cerys, Desai, Arpan, Sasso, Luana, Watson, Susan A., Alexander, Cameron
Format: Article
Language:English
Published: Royal Society of Chemistry 2015
Online Access:http://eprints.nottingham.ac.uk/39081/
http://eprints.nottingham.ac.uk/39081/
http://eprints.nottingham.ac.uk/39081/
http://eprints.nottingham.ac.uk/39081/1/Grabowska%20systemic.pdf