Synthesis of 19F nucleic acid–polymer conjugates as real-time MRI probes of biorecognition
Polymer–DNA conjugates in which one nucleic acid strand contains fluorine-substituted nucleobases have been prepared and characterised. The efficacy of these novel 19F nucleic acid–polymer conjugates as sensitive and selective in vitro reporters of DNA binding events is demonstrated through a number...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Royal Society of Chemistry
2016
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Online Access: | http://eprints.nottingham.ac.uk/38823/ http://eprints.nottingham.ac.uk/38823/ http://eprints.nottingham.ac.uk/38823/ http://eprints.nottingham.ac.uk/38823/1/Article_G.Sicilia%20revised.pdf |