Suberanilohydroxamic acid (SAHA) inhibits collagen deposition in a transforming growth factor β1-driven precision cut lung slice (PCLS) model of pulmonary fibrosis
Introduction and Objectives: Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive interstitial lung disease that is refractory to current treatment options. Transforming growth factor (TGF)-β1 is a key pro-fibrotic cytokine that plays a crucial role in IPF pathogenesis. Our group previously...
Main Authors: | , , , , , |
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Format: | Conference or Workshop Item |
Language: | English |
Published: |
2016
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Online Access: | http://eprints.nottingham.ac.uk/38772/ http://eprints.nottingham.ac.uk/38772/1/BTS-Abstract-Final.pdf |