The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high energy phosphate metabolism
Hypoxia-inducible factor (HIF) appears to function as a global master regulator of cellular and systemic responses to hypoxia. HIF-pathway manipulation is of therapeutic interest, however global, systemic upregulation of HIF may have as yet unknown effects on multiple processes. We utilized a mouse...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Physiological Society
2016
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| Online Access: | http://eprints.nottingham.ac.uk/34954/ http://eprints.nottingham.ac.uk/34954/ http://eprints.nottingham.ac.uk/34954/ http://eprints.nottingham.ac.uk/34954/1/Slingo_accepted_MS_AJP_120716.pdf |