Systematic critical review of previous economic evaluations of smoking cessation during pregnancy

Objective: To identify and critically assess previous economic evaluations of smoking cessation interventions delivered during pregnancy. Design: Qualitative review of studies with primary data collection or hypothetical modelling. Quality assessed using the Quality of Health Economic Studies che...

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Main Authors: Jones, Matthew, Lewis, Sarah, Parrott, Steve, Coleman, Tim
Format: Article
Language:English
Published: BMJ Publishing Group Ltd 2015
Online Access:http://eprints.nottingham.ac.uk/31210/
http://eprints.nottingham.ac.uk/31210/
http://eprints.nottingham.ac.uk/31210/
http://eprints.nottingham.ac.uk/31210/1/BMJ%20Open-2015-Jones-.pdf
id nottingham-31210
recordtype eprints
spelling nottingham-312102018-06-26T12:31:27Z http://eprints.nottingham.ac.uk/31210/ Systematic critical review of previous economic evaluations of smoking cessation during pregnancy Jones, Matthew Lewis, Sarah Parrott, Steve Coleman, Tim Objective: To identify and critically assess previous economic evaluations of smoking cessation interventions delivered during pregnancy. Design: Qualitative review of studies with primary data collection or hypothetical modelling. Quality assessed using the Quality of Health Economic Studies checklist. Data sources: Electronic search of 13 databases including Medline, Econlit, Embase, and PubMed, and manual search of the UK's National Institute of Health and Care Excellence guidelines and US Surgeon General. Eligibility criteria for selecting studies: All study designs considered if they were published in English, evaluated a cessation intervention delivered to pregnant women during pregnancy, and reported any relevant economic evaluation metric (eg, cost per quitter, incremental cost per quality adjusted life year). Results: 18 studies were included. 18 evaluations were conducted alongside clinical trials, four were part of observational studies, five were hypothetical decision-analytic models and one combined modelling with within-trial analysis. Analyses conducted were cost-offset (nine studies), cost-effectiveness (five studies), cost-utility (two studies), and combined cost-effectiveness and cost-utility (two studies). Six studies each were identified as high, fair and poor quality, respectively. All interventions were demonstrated to be cost-effective except motivational interviewing which was dominated by usual care (one study). Areas where the current literature was limited were the robust investigation of uncertainty, including time horizons that included outcomes beyond the end of pregnancy, including major morbidities for the mother and her infant, and incorporating better estimates of postpartum relapse. Conclusions: There are relatively few high quality economic evaluations of cessation interventions during pregnancy. The majority of the literature suggests that such interventions offer value for money; however, there are methodological issues that require addressing, including investigating uncertainty more robustly, utilising better estimates for postpartum relapse, extending beyond a within-pregnancy time horizon, and including major morbidities for the mother and her infant for within-pregnancy and beyond. BMJ Publishing Group Ltd 2015-11-13 Article PeerReviewed application/pdf en http://eprints.nottingham.ac.uk/31210/1/BMJ%20Open-2015-Jones-.pdf Jones, Matthew and Lewis, Sarah and Parrott, Steve and Coleman, Tim (2015) Systematic critical review of previous economic evaluations of smoking cessation during pregnancy. BMJ Open, 5 (11). e008998. ISSN 2044-6055 http://bmjopen.bmj.com/content/5/11/e008998.full doi:10.1136/bmjopen-2015-008998 doi:10.1136/bmjopen-2015-008998
repository_type Digital Repository
institution_category Local University
institution University of Nottingham Malaysia Campus
building Nottingham Research Data Repository
collection Online Access
language English
description Objective: To identify and critically assess previous economic evaluations of smoking cessation interventions delivered during pregnancy. Design: Qualitative review of studies with primary data collection or hypothetical modelling. Quality assessed using the Quality of Health Economic Studies checklist. Data sources: Electronic search of 13 databases including Medline, Econlit, Embase, and PubMed, and manual search of the UK's National Institute of Health and Care Excellence guidelines and US Surgeon General. Eligibility criteria for selecting studies: All study designs considered if they were published in English, evaluated a cessation intervention delivered to pregnant women during pregnancy, and reported any relevant economic evaluation metric (eg, cost per quitter, incremental cost per quality adjusted life year). Results: 18 studies were included. 18 evaluations were conducted alongside clinical trials, four were part of observational studies, five were hypothetical decision-analytic models and one combined modelling with within-trial analysis. Analyses conducted were cost-offset (nine studies), cost-effectiveness (five studies), cost-utility (two studies), and combined cost-effectiveness and cost-utility (two studies). Six studies each were identified as high, fair and poor quality, respectively. All interventions were demonstrated to be cost-effective except motivational interviewing which was dominated by usual care (one study). Areas where the current literature was limited were the robust investigation of uncertainty, including time horizons that included outcomes beyond the end of pregnancy, including major morbidities for the mother and her infant, and incorporating better estimates of postpartum relapse. Conclusions: There are relatively few high quality economic evaluations of cessation interventions during pregnancy. The majority of the literature suggests that such interventions offer value for money; however, there are methodological issues that require addressing, including investigating uncertainty more robustly, utilising better estimates for postpartum relapse, extending beyond a within-pregnancy time horizon, and including major morbidities for the mother and her infant for within-pregnancy and beyond.
format Article
author Jones, Matthew
Lewis, Sarah
Parrott, Steve
Coleman, Tim
spellingShingle Jones, Matthew
Lewis, Sarah
Parrott, Steve
Coleman, Tim
Systematic critical review of previous economic evaluations of smoking cessation during pregnancy
author_facet Jones, Matthew
Lewis, Sarah
Parrott, Steve
Coleman, Tim
author_sort Jones, Matthew
title Systematic critical review of previous economic evaluations of smoking cessation during pregnancy
title_short Systematic critical review of previous economic evaluations of smoking cessation during pregnancy
title_full Systematic critical review of previous economic evaluations of smoking cessation during pregnancy
title_fullStr Systematic critical review of previous economic evaluations of smoking cessation during pregnancy
title_full_unstemmed Systematic critical review of previous economic evaluations of smoking cessation during pregnancy
title_sort systematic critical review of previous economic evaluations of smoking cessation during pregnancy
publisher BMJ Publishing Group Ltd
publishDate 2015
url http://eprints.nottingham.ac.uk/31210/
http://eprints.nottingham.ac.uk/31210/
http://eprints.nottingham.ac.uk/31210/
http://eprints.nottingham.ac.uk/31210/1/BMJ%20Open-2015-Jones-.pdf
first_indexed 2018-09-06T12:07:11Z
last_indexed 2018-09-06T12:07:11Z
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