Catalytic reductive N-alkylation of amines using carboxylic acids

We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction.

Bibliographic Details
Main Authors: Andrews, Keith Gordon, Summers, Declan, Donnelly, Liam, Denton, Ross Matthew
Format: Article
Language:English
Published: Royal Society of Chemistry 2015
Online Access:http://eprints.nottingham.ac.uk/31067/
http://eprints.nottingham.ac.uk/31067/
http://eprints.nottingham.ac.uk/31067/
http://eprints.nottingham.ac.uk/31067/1/Denton%20paper%20for%20Nottingham%20ePrints.pdf