The influence of bioreactor geometry and the mechanical environment on engineered tissues

A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. The cell population (and attendant extracellular matrix), culture medium and porous scaffold are treated as distinct phases. The bioreactor system is represented by a two-dimensional channel containin...

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Bibliographic Details
Main Authors: Osborne, J.M., O'Dea, Reuben D., Whiteley, J.P., Byrne, H.M., Waters, S.L.
Format: Article
Language:English
Published: American Society of Mechanical Engineers 2010
Online Access:http://eprints.nottingham.ac.uk/29049/
http://eprints.nottingham.ac.uk/29049/
http://eprints.nottingham.ac.uk/29049/
http://eprints.nottingham.ac.uk/29049/1/odeaosbornewhiteleybyrnewaters.pdf