Statistical inference of in vivo properties of human DNA methyltransferases from double-stranded methylation patterns
DNA methyltransferases establish methylation patterns in cells and transmit these patterns over cell generations, thereby influencing each cell's epigenetic states. Three primary DNA methyltransferases have been identified in mammals: DNMT1, DNMT3A and DNMT3B. Extensive in vitro studies have in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2012
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| Online Access: | http://eprints.nottingham.ac.uk/2604/ http://eprints.nottingham.ac.uk/2604/ http://eprints.nottingham.ac.uk/2604/ http://eprints.nottingham.ac.uk/2604/1/StogerStatistical.pdf |