Asymmetric rhodium catalysed additions to activated imines : new approaches to α-chiral amines

This Thesis details the development of a series of rhodium catalysed asymmetric additions to activated aldimines to give enantioenriched protected secondary amines. A particular focus has been the choice of activating group to allow deprotection of the protected amines under mild conditions, which w...

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Bibliographic Details
Main Author: Crampton, Rosemary Helen
Format: Thesis (University of Nottingham only)
Language:English
Published: 2012
Online Access:http://eprints.nottingham.ac.uk/12929/
http://eprints.nottingham.ac.uk/12929/1/Thesis_final.pdf