SQSTM1 mutations and Paget's disease of bone
Mutations affecting the p62 signalling adapter protein are commonly found in patients with the skeletal disorder Paget‟s disease of bone (PDB). We have extended previous in vitro functional analyses of PDB-mutant p62 proteins (Cavey et al., 2006) to study the effects of several uncharacterised PDB-a...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2010
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| Online Access: | http://eprints.nottingham.ac.uk/11118/ http://eprints.nottingham.ac.uk/11118/1/Dereen_najat_final_copy_PhD_THESIS_2010.pdf |