Molecular Basis of CYP2B2 Induction
Many structurally unrelated chemicals can induce members of the cytochrome P450 superfamily with phenobarbital (PB) being a typical example. PB induces CYP2B1/2, which are most highly expressed in the liver. Their mechanism of activation has not yet been elucidated, with advances hampered by the abs...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
1999
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| Online Access: | http://eprints.nottingham.ac.uk/10397/ http://eprints.nottingham.ac.uk/10397/1/Neill.pdf |