Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach

Momorica charantia fruit is one of the herbal plants and food used in Malaysia known as “Peria katak”. This plant has been used traditionally to relieve some disease including diabetes, ulcer, gout, and cough. This study focused on the identification of potential antioxidants in this fruit using GC-...

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Main Authors:	Perumal, Vikneswari, Uzir, Bisha Fathamah, Abas, Faridah, Ahmed, Qamar Uddin, Nik Yusoff, Nik Mohd. Idris, Khatib, Alfi
Format:	Conference or Workshop Item
Language:	English
Published:	2016
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/50626/ http://irep.iium.edu.my/50626/3/50626.pdf

id	iium-50626
recordtype	eprints
spelling	iium-506262016-07-18T13:52:30Z http://irep.iium.edu.my/50626/ Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach Perumal, Vikneswari Uzir, Bisha Fathamah Abas, Faridah Ahmed, Qamar Uddin Nik Yusoff, Nik Mohd. Idris Khatib, Alfi QD Chemistry Momorica charantia fruit is one of the herbal plants and food used in Malaysia known as “Peria katak”. This plant has been used traditionally to relieve some disease including diabetes, ulcer, gout, and cough. This study focused on the identification of potential antioxidants in this fruit using GC-MS based metabolomics approach. Six series of solvents including water, 40%, 60%, 80% ethanol in water, and ethanol was used to extract the fruit. GC-MS profiles combined with antioxidant activities (DPPH and FRAP) were calculated using orthogonal partial least square to identify which retention times in GC-MS chromatogram correlate to antioxidant activities. This information was submitted to the NIST database to elucidate which compounds were present. The score plot showed an obvious and remarkable separation into six clusters indicating the six different of metabolite profile of the extracts. The results revealed 8 compounds in this fruit induce the antioxidant activities, while 2 others suppress the bio-activities. 2016-03-15 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/50626/3/50626.pdf Perumal, Vikneswari and Uzir, Bisha Fathamah and Abas, Faridah and Ahmed, Qamar Uddin and Nik Yusoff, Nik Mohd. Idris and Khatib, Alfi (2016) Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach. In: International Conference on Natural Products 2016 (ICNP 2016), 15th-17th March 2016, Kuala Terengganu, Terengganu, Malaysia. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Perumal, Vikneswari Uzir, Bisha Fathamah Abas, Faridah Ahmed, Qamar Uddin Nik Yusoff, Nik Mohd. Idris Khatib, Alfi Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach
description	Momorica charantia fruit is one of the herbal plants and food used in Malaysia known as “Peria katak”. This plant has been used traditionally to relieve some disease including diabetes, ulcer, gout, and cough. This study focused on the identification of potential antioxidants in this fruit using GC-MS based metabolomics approach. Six series of solvents including water, 40%, 60%, 80% ethanol in water, and ethanol was used to extract the fruit. GC-MS profiles combined with antioxidant activities (DPPH and FRAP) were calculated using orthogonal partial least square to identify which retention times in GC-MS chromatogram correlate to antioxidant activities. This information was submitted to the NIST database to elucidate which compounds were present. The score plot showed an obvious and remarkable separation into six clusters indicating the six different of metabolite profile of the extracts. The results revealed 8 compounds in this fruit induce the antioxidant activities, while 2 others suppress the bio-activities.
format	Conference or Workshop Item
author	Perumal, Vikneswari Uzir, Bisha Fathamah Abas, Faridah Ahmed, Qamar Uddin Nik Yusoff, Nik Mohd. Idris Khatib, Alfi
author_facet	Perumal, Vikneswari Uzir, Bisha Fathamah Abas, Faridah Ahmed, Qamar Uddin Nik Yusoff, Nik Mohd. Idris Khatib, Alfi
author_sort	Perumal, Vikneswari
title	Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach
title_short	Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach
title_full	Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach
title_fullStr	Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach
title_full_unstemmed	Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach
title_sort	identification of antioxidants in momordica charantia fruit using gc-ms metabolomics approach
publishDate	2016
url	http://irep.iium.edu.my/50626/ http://irep.iium.edu.my/50626/3/50626.pdf
first_indexed	2018-09-07T07:03:36Z
last_indexed	2018-09-07T07:03:36Z
_version_	1610931310522531840

Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach

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