Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection

Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection

Abstract Background Staphylococcus aureus (S. aureus) causes a wide range of infectious diseases in human and animals. The emergence of antibiotic-resistant strains demands novel strategies for prophylactic vaccine development. In this study, live attenuated S. enterica subsp. enterica serotype Typh...

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Bibliographic Details
Main Authors: Chen Xu, Bao-zhong Zhang, Qiubin Lin, Jian Deng, Bin Yu, Smriti Arya, Kwok-Yung Yuen, Jian-Dong Huang
Format: Article
Language:English
Published: BioMed Central 2018-04-01
Series:BMC Infectious Diseases
Subjects:
Live attenuated S. Typhimurium vaccine
T3SS
MRSA
S. aureus
SaEsxA
SaEsxB
Online Access:http://link.springer.com/article/10.1186/s12879-018-3104-y

Internet

http://link.springer.com/article/10.1186/s12879-018-3104-y

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