Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

Abstract Hutchinson-Gilford progeria syndrome (HGPS) and Werner syndrome (WS) are two of the best characterized human progeroid syndromes. HGPS is caused by a point mutation in lamin A (LMNA) gene, resulting in the production of a truncated protein product—progerin. WS is caused by mutations in WRN...

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Bibliographic Details
Main Authors: Zeming Wu, Weiqi Zhang, Moshi Song, Wei Wang, Gang Wei, Wei Li, Jinghui Lei, Yu Huang, Yanmei Sang, Piu Chan, Chang Chen, Jing Qu, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Guang-Hui Liu
Format: Article
Language:English
Published: Springer 2018-02-01
Series:Protein & Cell
Subjects:
WRN
lamin
HGPS
Werner syndrome
stem cell
aging
Online Access:http://link.springer.com/article/10.1007/s13238-018-0517-8

Internet

http://link.springer.com/article/10.1007/s13238-018-0517-8

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