Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

Abstract The Tasmanian devil faces extinction due to devil facial tumour disease (DFTD), a highly transmittable clonal form of cancer without available treatment. In this study, we report the cell-autonomous antiproliferative and cytotoxic activities exhibited by the spider peptide gomesin (AgGom) a...

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Bibliographic Details
Main Authors: Manuel A. Fernandez-Rojo, Evelyne Deplazes, Sandy S. Pineda, Andreas Brust, Tano Marth, Patrick Wilhelm, Nick Martel, Grant A. Ramm, Ricardo L. Mancera, Paul F. Alewood, Gregory M. Woods, Katherine Belov, John J. Miles, Glenn F. King, Maria P. Ikonomopoulou
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Cell Death Discovery
Online Access:http://link.springer.com/article/10.1038/s41420-018-0030-0