Dehydrogenative reagent-free annulation of alkenes with diols for the synthesis of saturated O-heterocycles
Dehydrogenative annulation is a valuable approach to heterocycles, however, stoichiometric oxidants are often required. Here, the authors describe the electrochemical dehydrogenative annulation of diols and alkenes to generate dioxanes and dioxepanes under metal- and oxidant-free conditions.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-09-01
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| Series: | Nature Communications |
| Online Access: | http://link.springer.com/article/10.1038/s41467-018-06020-8 |