Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-κB/Snail signaling pathway

Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-κB/Snail signaling pathway

Abstract Background Parthenolide (PTL) is a natural molecule isolated from Tanacetum parthenium that exhibits excellent anti-inflammatory and antitumor activities. Pulmonary fibrosis (PF), especially idiopathic pulmonary fibrosis (IPF), is a chronic lung disease that lacks a proven effective therapy...

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Bibliographic Details
Main Authors: Xiao-he Li, Ting Xiao, Jia-huan Yang, Yuan Qin, Jing-jing Gao, Hui-juan Liu, Hong-gang Zhou
Format: Article
Language:English
Published: BioMed Central 2018-06-01
Series:Respiratory Research
Subjects:
Parthenolide
Pulmonary fibrosis
NF-κB/Snail signaling pathway
Online Access:http://link.springer.com/article/10.1186/s12931-018-0806-z

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