Protective effects of γ-aminobutyric acid against H2O2-induced oxidative stress in RIN-m5F pancreatic cells

Protective effects of γ-aminobutyric acid against H2O2-induced oxidative stress in RIN-m5F pancreatic cells

Abstract Background γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the central nervous system and reported to maintain the redox homeostasis and insulin secretion function of pancreatic β cells. This study tested the hypothesis that GABA maintains cellular redox status, and mod...

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Bibliographic Details
Main Authors: Xue Tang, Renqiang Yu, Qin Zhou, Shanyu Jiang, Guowei Le
Format: Article
Language:English
Published: BioMed Central 2018-09-01
Series:Nutrition & Metabolism
Subjects:
GABA
Anti-oxidation
Anti-apoptosis
Insulin secretion
RINm5f cells
Online Access:http://link.springer.com/article/10.1186/s12986-018-0299-2

Internet

http://link.springer.com/article/10.1186/s12986-018-0299-2

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