Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-γ stimulated macrophages

Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-γ stimulated macrophages

<p>Azithromycin (AZM), a 15-member macrolide antibiotic, possesses anti-inflammatory activity. Macrophages are important in innate and acquired immunity, and produce pro-inflammatory cytokines such as interleukin (IL)-12, which are composed of subunit p40 and p35. The key function of IL-12 is...

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Bibliographic Details
Main Author: Keiko Yamauchi, Yoko Shibata, Tomomi Kimura, Shuichi Abe, Sumito Inoue, Daisuke Osaka, Michiko Sato, Akira Igarashi, Isao Kubota
Format: Article
Language:English
Published: Ivyspring International Publisher 2009-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v05p0667.htm

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http://www.biolsci.org/v05p0667.htm

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