Structural basis of cell wall peptidoglycan amidation by the GatD/MurT complex of Staphylococcus aureus
Abstract The peptidoglycan of Staphylococcus aureus is highly amidated. Amidation of α-D-isoglutamic acid in position 2 of the stem peptide plays a decisive role in the polymerization of cell wall building blocks. S. aureus mutants with a reduced degree of amidation are less viable and show increase...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-08-01
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| Series: | Scientific Reports |
| Online Access: | http://link.springer.com/article/10.1038/s41598-018-31098-x |