Analysis of the effect of S-gene N-glycosylation mutations of HBV from patients with occult HBV infection on HBsAg antigenicity

Analysis of the effect of S-gene N-glycosylation mutations of HBV from patients with occult HBV infection on HBsAg antigenicity

Objective　To analyze antigenicity of N-glycosylation mutations in the major hydrophilic region (MHR) of HBV S gene from patients with occult HBV infection (OBI), and reveal the relationship of these mutations with mechanism of OBI presentation and its clinical significance. Methods　Four mutations wi...

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Bibliographic Details
Main Authors: Yan LIU, Kai ZHANG, Rong-juan CHEN, Qi LI, Zhi-hui XU, Lan-lan SI, Shu-mei LIN, Dong-ping XU
Format: Article
Language:Chinese
Published: Editorial Board of Medical Journal of Chinese People's Liberation Army 2018-05-01
Series:Medical Journal of Chinese People's Liberation Army
Subjects:
hepatitis B virus
S gene
mutation
N-glycosylation
antigenicity
Online Access:http://www.plamj.org/index.php/plamj/article/view/1778

Internet

http://www.plamj.org/index.php/plamj/article/view/1778

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