A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti.
Ototoxicity is a significant side effect of a number of drugs, including the aminoglycoside antibiotics and platinum-based chemotherapeutic agents that are used to treat life-threatening illnesses. Although much progress has been made, the mechanisms that lead to ototoxic loss of inner ear sensory h...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5648133?pdf=render |