Boldine Ameliorates Estrogen Deficiency-Induced Bone Loss via Inhibiting Bone Resorption

Boldine Ameliorates Estrogen Deficiency-Induced Bone Loss via Inhibiting Bone Resorption

Osteoporosis is an enormous health problem caused by the imbalance between bone resorption and bone formation. The current therapeutic strategies for osteoporosis still have some limitations. Boldine, an alkaloid isolated from Peumus boldus, has been shown to have antioxidant and anti-inflammatory e...

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Bibliographic Details
Main Authors: Kun Chen, Zheng-tao Lv, Peng Cheng, Wen-tao Zhu, Shuang Liang, Qing Yang, Virginia-Jeni Akila Parkman, Chen-he Zhou, Xing-zhi Jing, Hui Liu, Yu-ting Wang, Hui Lin, Hui Liao, An-min Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
boldine
osteoporosis
osteoclast
osteoblast
AKT
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01046/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01046/full

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