The Role of the Transcription Factor Nuclear Factor-kappa B in Thyroid Autoimmunity and Cancer

The Role of the Transcription Factor Nuclear Factor-kappa B in Thyroid Autoimmunity and Cancer

Nuclear factor-kappa B (NF-κB) is a ubiquitous transcription factor that is involved in inflammatory and immune responses, as well as in regulation of expression of many other genes related to cell survival, proliferation, and differentiation. In mammals, NF-κB comprises five subunits that can bind...

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Bibliographic Details
Main Authors: Cesidio Giuliani, Ines Bucci, Giorgio Napolitano
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Endocrinology
Subjects:
NF-κB
thyroid autoimmunity
thyroid cancer
transcription factors
gene regulation
major histocompatibility complex
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00471/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00471/full

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