Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease

Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease

Alzheimer's disease (AD) is the most common form of dementia in the older population, however, the precise cause of the disease is unknown. The neuropathology is characterized by the presence of aggregates formed by amyloid-β (Aβ) peptide and phosphorylated tau; which is accompanied by progress...

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Bibliographic Details
Main Authors: Cheril Tapia-Rojas, Nibaldo C Inestrosa
Format: Article
Language:English
Published: Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
Wnt signaling; Wnt target genes; Wnt/β-catenin; Alzheimer disease; amyloid-β; tau phosphorylation; memory loss; synaptic dysfunction
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=10;spage=1705;epage=1710;aulast=Tapia-Rojas

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=10;spage=1705;epage=1710;aulast=Tapia-Rojas

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