The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells

The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells

Abstract Pigment epithelium derived factor (PEDF), a ubiquitously expressed 50 kDa secreted glycoprotein, was recently discovered to regulate self-renewal of neural stem cells and have a supportive effect on human embryonic stem cell growth. Here, we analyzed expression of PEDF in the murine hematop...

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Bibliographic Details
Main Authors: Emma Rörby, Matilda Billing, Maria Dahl, Sarah Warsi, Silja Andradottir, Kenichi Miharada, Kavitha Siva, Jan-Ingvar Jönsson, Ulrika Blank, Göran Karlsson, Stefan Karlsson
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:http://link.springer.com/article/10.1038/s41598-017-09452-2

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http://link.springer.com/article/10.1038/s41598-017-09452-2

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