Mutations in dock1 disrupt early Schwann cell development

Abstract Background In the peripheral nervous system (PNS), specialized glial cells called Schwann cells produce myelin, a lipid-rich insulating sheath that surrounds axons and promotes rapid action potential propagation. During development, Schwann cells must undergo extensive cytoskeletal rearrang...

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Bibliographic Details
Main Authors: Rebecca L. Cunningham, Amy L. Herbert, Breanne L. Harty, Sarah D. Ackerman, Kelly R. Monk
Format: Article
Language:English
Published: BioMed Central 2018-08-01
Series:Neural Development
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13064-018-0114-9