Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis

Abstract Mechanisms of injury and repair in alveolar epithelial cells (AECs) are critically involved in the progression of various lung diseases including idiopathic pulmonary fibrosis (IPF). Homeobox only protein x (HOPX) contributes to the formation of distal lung during development. In adult lung...

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Bibliographic Details
Main Authors: Chiharu Ota, John-Poul Ng-Blichfeldt, Martina Korfei, Hani N. Alsafadi, Mareike Lehmann, Wioletta Skronska-Wasek, Martina M. De Santis, Andreas Guenther, Darcy E. Wagner, Melanie Königshoff
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:http://link.springer.com/article/10.1038/s41598-018-31214-x