Hybrid assembly with long and short reads improves discovery of gene family expansions

Hybrid assembly with long and short reads improves discovery of gene family expansions

Abstract Background Long-read and short-read sequencing technologies offer competing advantages for eukaryotic genome sequencing projects. Combinations of both may be appropriate for surveys of within-species genomic variation. Methods We developed a hybrid assembly pipeline called “Alpaca” that can...

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Bibliographic Details
Main Authors: Jason R. Miller, Peng Zhou, Joann Mudge, James Gurtowski, Hayan Lee, Thiruvarangan Ramaraj, Brian P. Walenz, Junqi Liu, Robert M. Stupar, Roxanne Denny, Li Song, Namrata Singh, Lyza G. Maron, Susan R. McCouch, W. Richard McCombie, Michael C. Schatz, Peter Tiffin, Nevin D. Young, Kevin A. T. Silverstein
Format: Article
Language:English
Published: BioMed Central 2017-07-01
Series:BMC Genomics
Subjects:
Genome assembly
Hybrid assembly pipeline
Tandem repeats
Medicago truncatula
Online Access:http://link.springer.com/article/10.1186/s12864-017-3927-8

Internet

http://link.springer.com/article/10.1186/s12864-017-3927-8

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