A cross-sectional study to evaluate second line virological failure and elevated bilirubin as a surrogate for adherence to atazanavir/ritonavir in two urban HIV clinics in Lilongwe, Malawi

A cross-sectional study to evaluate second line virological failure and elevated bilirubin as a surrogate for adherence to atazanavir/ritonavir in two urban HIV clinics in Lilongwe, Malawi

Abstract Background Malawi’s national antiretroviral therapy program provides atazanavir/ritonavir–based second line regimens which cause concentration-dependent rise in indirect bilirubin. We sought to determine if elevated bilirubin, as a surrogate of atazanavir/ritonavir adherence, can aid in the...

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Bibliographic Details
Main Authors: Dennis Miyoge Ongubo, Robertino Lim, Hannock Tweya, Christopher Chikhosi Stanley, Petros Tembo, Richard Broadhurst, Salem Gugsa, McNeil Ngongondo, Colin Speight, Tom Heller, Sam Phiri, Mina C. Hosseinipour
Format: Article
Language:English
Published: BioMed Central 2017-07-01
Series:BMC Infectious Diseases
Subjects:
Virological failure
Atazanavir/ritonavir
Second line
Antiretroviral therapy
Bilirubin
Adherence
Online Access:http://link.springer.com/article/10.1186/s12879-017-2528-0

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http://link.springer.com/article/10.1186/s12879-017-2528-0

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