Therapeutic Strategies for Targeting IL-33/ST2 Signalling for the Treatment of Inflammatory Diseases
Interleukin (IL)-33, a member of the IL-1 family of cytokines, is involved in innate and adaptive immune responses via interaction with its receptor, ST2. Activation of ST2 signalling by IL-33 triggers pleiotropic immune functions in multiple ST2-expressing immune cells, including macrophages, neutr...
Main Authors: | Wei-Yu Chen, Tzu-Hsien Tsai, Jenq-Lin Yang, Lung-Chih Li |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2018-08-01
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Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/492885 |
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