Therapeutic Strategies for Targeting IL-33/ST2 Signalling for the Treatment of Inflammatory Diseases

Interleukin (IL)-33, a member of the IL-1 family of cytokines, is involved in innate and adaptive immune responses via interaction with its receptor, ST2. Activation of ST2 signalling by IL-33 triggers pleiotropic immune functions in multiple ST2-expressing immune cells, including macrophages, neutr...

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Bibliographic Details
Main Authors: Wei-Yu Chen, Tzu-Hsien Tsai, Jenq-Lin Yang, Lung-Chih Li
Format: Article
Language:English
Published: Karger Publishers 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:https://www.karger.com/Article/FullText/492885

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