Monocytes-derived macrophages mediated stable expression of human brain-derived neurotrophic factor, a novel therapeutic strategy for neuroAIDS.

HIV-1 associated dementia remains a significant public health burden. Clinical and experimental research has shown that reduced levels of brain-derived neurotrophic factor (BDNF) may be a risk factor for neurological complications associated with HIV-1 infection. We are actively testing genetically...

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Bibliographic Details
Main Authors: Jing Tong, Shilpa Buch, Honghong Yao, Chengxiang Wu, Hsin-I Tong, Youwei Wang, Yuanan Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS)
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914783?pdf=render