HLAscan: genotyping of the HLA region using next-generation sequencing data

HLAscan: genotyping of the HLA region using next-generation sequencing data

Abstract Background Several recent studies showed that next-generation sequencing (NGS)-based human leukocyte antigen (HLA) typing is a feasible and promising technique for variant calling of highly polymorphic regions. To date, however, no method with sufficient read depth has completely solved the...

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Bibliographic Details
Main Authors: Sojeong Ka, Sunho Lee, Jonghee Hong, Yangrae Cho, Joohon Sung, Han-Na Kim, Hyung-Lae Kim, Jongsun Jung
Format: Article
Language:English
Published: BioMed Central 2017-05-01
Series:BMC Bioinformatics
Subjects:
HLA typing
Next-generation sequencing
Phasing issue
HLAscan
Online Access:http://link.springer.com/article/10.1186/s12859-017-1671-3

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http://link.springer.com/article/10.1186/s12859-017-1671-3

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