Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis

Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis

Abstract Background MP4-induced experimental autoimmune encephalomyelitis (EAE) is a mouse model of multiple sclerosis (MS), which enables targeted research on B cells, currently much discussed protagonists in MS pathogenesis. Here, we used this model to study the impact of the S1P1 receptor modulat...

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Bibliographic Details
Main Authors: Kathrin Bail, Quirin Notz, Damiano M. Rovituso, Andrea Schampel, Marie Wunsch, Tobias Koeniger, Verena Schropp, Richa Bharti, Claus-Juergen Scholz, Konrad U. Foerstner, Christoph Kleinschnitz, Stefanie Kuerten
Format: Article
Language:English
Published: BioMed Central 2017-07-01
Series:Journal of Neuroinflammation
Subjects:
B cells
EAE
Fingolimod
FTY720
Multiple sclerosis
TLO
Online Access:http://link.springer.com/article/10.1186/s12974-017-0924-4

Internet

http://link.springer.com/article/10.1186/s12974-017-0924-4

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