Elucidating the transactivation domain of the pleiotropic transcription factor Myrf

Abstract Myrf is a newly discovered membrane-bound transcription factor that plays an essential role in as diverse organisms as human, worm, and slime mold. Myrf is generated as a type-II membrane protein in the endoplasmic reticulum (ER). It forms homo-oligomers to undergo auto-cleavage that releas...

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Bibliographic Details
Main Authors: Jin-ok Choi, Chuandong Fan, Dongkyeong Kim, Mohamed Sharif, Hongjoo An, Yungki Park
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:http://link.springer.com/article/10.1038/s41598-018-31477-4