Antiproliferative factor (APF) binds specifically to sites within the cytoskeleton-associated protein 4 (CKAP4) extracellular domain

Antiproliferative factor (APF) binds specifically to sites within the cytoskeleton-associated protein 4 (CKAP4) extracellular domain

Abstract Background Antiproliferative factor (APF) is a sialoglycopeptide elevated in the urine of patients with interstitial cystitis—a chronic, painful bladder disease. APF inhibits the proliferation of normal bladder epithelial cells and cancer cells in vitro, presumably by binding to its cellula...

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Bibliographic Details
Main Authors: Burzin Chavda, Jun Ling, Thomas Majernick, Sonia Lobo Planey
Format: Article
Language:English
Published: BioMed Central 2017-09-01
Series:BMC Biochemistry
Subjects:
CKAP4
APF
Surface plasmon resonance (SPR)
Biomarker
Interstitial cystitis
Biosensor
Online Access:http://link.springer.com/article/10.1186/s12858-017-0088-y

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http://link.springer.com/article/10.1186/s12858-017-0088-y

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