Silibinin Ameliorates O-GlcNAcylation and Inflammation in a Mouse Model of Nonalcoholic Steatohepatitis

Silibinin Ameliorates O-GlcNAcylation and Inflammation in a Mouse Model of Nonalcoholic Steatohepatitis

The mechanisms underlying the progression to non-alcoholic steatohepatitis (NASH) remain to be elucidated. In the present study, we aimed to identify the proteins involved in the pathogenesis of liver tissue inflammation and to investigate the effects of silibinin, a natural polyphenolic flavonoid,...

Full description

Bibliographic Details
Main Authors: Su Jin Lee, Min Jung Nam, Da Eun Lee, Jeen-Woo Park, Beom Sik Kang, Dong-Seok Lee, Hyun-Shik Lee, Oh-Shin Kwon
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
silibinin
O-GlcNAcylation
non-alcoholic steatohepatitis
proteomics
inflammation
Online Access:http://www.mdpi.com/1422-0067/19/8/2165

Internet

http://www.mdpi.com/1422-0067/19/8/2165

Similar Items