Inhibition of HIV early replication by the p53 and its downstream gene p21

Inhibition of HIV early replication by the p53 and its downstream gene p21

Abstract Background The tumor suppressor gene p53 has been found to suppress HIV infection by various mechanisms, but the inhibition of HIV at an early stage of replication by host cell p53 and its downstream gene p21 has not been well studied. Method VSV-G pseudotyped HIV-1 or HIV-2 viruses with GF...

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Bibliographic Details
Main Authors: Binshan Shi, Hamayun J. Sharifi, Sara DiGrigoli, Michaela Kinnetz, Katie Mellon, Wenwei Hu, Carlos M. C. de Noronha
Format: Article
Language:English
Published: BioMed Central 2018-03-01
Series:Virology Journal
Subjects:
p53
p21
HIV-1
HIV-2
Reverse transcription
Cell cycle
Online Access:http://link.springer.com/article/10.1186/s12985-018-0959-x

Internet

http://link.springer.com/article/10.1186/s12985-018-0959-x

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