A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever

Background & objectives: We have established a severity grading score (SGS) system for predicting the fatalityin Crimean-Congo hemorrhagic fever (CCHF) for the first time.Methods: This SGS has been set up by using several variables which were assumed to be associated withmortality according to t...

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Main Author:	Mehmet Bakir , Aynur Engin , Mustafa Gokhan Gozel , Nazif Elaldi , Saadettin Kilickap & Ziynet Cinar
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2012-06-01
Series:	Journal of Vector Borne Diseases
Subjects:	Crimean-Congo hemorrhagic fever mortality severity grading score
Online Access:	http://www.mrcindia.org/journal/issues/492105.pdf

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spelling	doaj-art-95f45fff0d874264baaf85a78b5b1c192018-09-02T16:09:07ZengWolters Kluwer Medknow PublicationsJournal of Vector Borne Diseases0972-90622012-06-01492105110A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic feverMehmet Bakir , Aynur Engin , Mustafa Gokhan Gozel , Nazif Elaldi , Saadettin Kilickap & Ziynet CinarBackground & objectives: We have established a severity grading score (SGS) system for predicting the fatalityin Crimean-Congo hemorrhagic fever (CCHF) for the first time.Methods: This SGS has been set up by using several variables which were assumed to be associated withmortality according to the literature and also were considered to have clinical importance.Results: In all, 237 patients who had symptoms of CCHF for <5 days were included. The patients were groupedinto three categories according to the mortality risk by using SGS as follows : low or no risk, intermediate andhigh risk groups. A SGS <5 showed no association with mortality (there were 158 cases in this group and allsurvived). This group constituted 66.7% of all the patients with CCHF. A SGS 6–10 showed moderate risk ofmortality (10%) and seven out of 70 patients in this group died. SGS >11 means high risk for mortality (67%)and six out of 9 patients in this group died (p = 0.001). The sensitivity, specificity, accuracy, positive predictivevalue, and negative predictive value for >11 points of SGS were 67, 100, 98, 100, and 98%, respectively.Conclusions: This scoring system may help the clinicians to decide which patient to refer to a tertiary stephospital which may also decrease the cost and improve the functionality of healthcare staff.http://www.mrcindia.org/journal/issues/492105.pdfCrimean-Congo hemorrhagic fevermortalityseverity grading score
institution	Open Data Bank
collection	Open Access Journals
building	Directory of Open Access Journals
language	English
format	Article
author	Mehmet Bakir , Aynur Engin , Mustafa Gokhan Gozel , Nazif Elaldi , Saadettin Kilickap & Ziynet Cinar
spellingShingle	Mehmet Bakir , Aynur Engin , Mustafa Gokhan Gozel , Nazif Elaldi , Saadettin Kilickap & Ziynet Cinar A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever Journal of Vector Borne Diseases Crimean-Congo hemorrhagic fever mortality severity grading score
author_facet	Mehmet Bakir , Aynur Engin , Mustafa Gokhan Gozel , Nazif Elaldi , Saadettin Kilickap & Ziynet Cinar
author_sort	Mehmet Bakir , Aynur Engin , Mustafa Gokhan Gozel , Nazif Elaldi , Saadettin Kilickap & Ziynet Cinar
title	A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever
title_short	A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever
title_full	A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever
title_fullStr	A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever
title_full_unstemmed	A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever
title_sort	new perspective to determine the severity of cases with crimean-congo hemorrhagic fever
publisher	Wolters Kluwer Medknow Publications
series	Journal of Vector Borne Diseases
issn	0972-9062
publishDate	2012-06-01
description	Background & objectives: We have established a severity grading score (SGS) system for predicting the fatalityin Crimean-Congo hemorrhagic fever (CCHF) for the first time.Methods: This SGS has been set up by using several variables which were assumed to be associated withmortality according to the literature and also were considered to have clinical importance.Results: In all, 237 patients who had symptoms of CCHF for <5 days were included. The patients were groupedinto three categories according to the mortality risk by using SGS as follows : low or no risk, intermediate andhigh risk groups. A SGS <5 showed no association with mortality (there were 158 cases in this group and allsurvived). This group constituted 66.7% of all the patients with CCHF. A SGS 6–10 showed moderate risk ofmortality (10%) and seven out of 70 patients in this group died. SGS >11 means high risk for mortality (67%)and six out of 9 patients in this group died (p = 0.001). The sensitivity, specificity, accuracy, positive predictivevalue, and negative predictive value for >11 points of SGS were 67, 100, 98, 100, and 98%, respectively.Conclusions: This scoring system may help the clinicians to decide which patient to refer to a tertiary stephospital which may also decrease the cost and improve the functionality of healthcare staff.
topic	Crimean-Congo hemorrhagic fever mortality severity grading score
url	http://www.mrcindia.org/journal/issues/492105.pdf
_version_	1612635564308168704

A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever

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