Scaffolding of long read assemblies using long range contact information

Abstract Background Long read technologies have revolutionized de novo genome assembly by generating contigs orders of magnitude longer than that of short read assemblies. Although assembly contiguity has increased, it usually does not reconstruct a full chromosome or an arm of the chromosome, resul...

Full description

Bibliographic Details
Main Authors: Jay Ghurye, Mihai Pop, Sergey Koren, Derek Bickhart, Chen-Shan Chin
Format: Article
Language:English
Published: BioMed Central 2017-07-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-3879-z