Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany
Abstract Background This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower HRQoL independent of metabolic health status and potential confounders,...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BioMed Central
2017-06-01
|
| Series: | Health and Quality of Life Outcomes |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12955-017-0688-7 |
| id |
doaj-art-710b63d488114bfea9bb78c2068b45bb |
|---|---|
| recordtype |
oai_dc |
| spelling |
doaj-art-710b63d488114bfea9bb78c2068b45bb2018-08-16T00:07:52ZengBioMed CentralHealth and Quality of Life Outcomes1477-75252017-06-011511710.1186/s12955-017-0688-7Physical health-related quality of life in relation to metabolic health and obesity among men and women in GermanyJulia Truthmann0Gert B. M. Mensink1Anja Bosy-Westphal2Ulfert Hapke3Christa Scheidt-Nave4Anja Schienkiewitz5Department of Epidemiology and Health Monitoring, Robert Koch InstituteDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteInstitute of Nutritional Medicine, University of HohenheimDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteAbstract Background This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower HRQoL independent of metabolic health status and potential confounders, and (2) whether associations are similar in men and women. Methods We used cross-sectional data from the German Health Interview and Examination Survey 2008–11. Physical HRQoL was measured using the Short Form-36 version 2 physical component summary (PCS) score. Based on harmonized ATPIII criteria for the definition of the metabolic health and a body mass index ≥ 30 kg/m2 to define obesity, individuals were classified as metabolically healthy non-obese (MHNO), metabolically unhealthy non-obese (MUNO), metabolically healthy obese (MHO), and metabolically unhealthy obese (MUO). Sex-specific analyses including multivariable linear regression analyses were based on PCS as the dependent variable, metabolic health and obesity category as the independent variable with three categories and MHNO as the reference, and age, education, lifestyle and comorbidities as confounders. Results This study included 6860 participants (3298 men, 3562 women). Compared to MHNO, all other metabolic health and obesity categories had significantly lower PCS in both sexes. As reflected by the beta coefficients [95% confidence interval] from bivariable linear regression models, a significant inverse association with PCS was strongest for MUO (men: −7.0 [−8.2; −5.8]; women: −9.0 [−10.2; −7.9]), intermediate for MUNO (men: −4.2 [−5.3; −3.1]; women: −5.6 [−6.8; −4.4]) and least pronounced for MHO (men: −2.2 [−3.6; −0.8]; women −3.9 [−5.4; −2.5]). Differences in relation to MHNO remained statistically significant for all groups after adjusting for confounders, but decreased in particular for MUNO (men:–1.3 [−2.3; −0.3]; women: −1.5 [−2.7; −0.3]. Conclusions Obesity was significantly related to lower physical HRQoL, independent of metabolic health status. Potential confounders including age, educational status, health-related behaviors, and comorbidities explained parts of the inverse relationship. Associations were evident in both sexes and consistently more pronounced among women than men.http://link.springer.com/article/10.1186/s12955-017-0688-7Metabolically healthy obesitySF-36Physical component summarySexSocio-economic statusLifestyle |
| institution |
Open Data Bank |
| collection |
Open Access Journals |
| building |
Directory of Open Access Journals |
| language |
English |
| format |
Article |
| author |
Julia Truthmann Gert B. M. Mensink Anja Bosy-Westphal Ulfert Hapke Christa Scheidt-Nave Anja Schienkiewitz |
| spellingShingle |
Julia Truthmann Gert B. M. Mensink Anja Bosy-Westphal Ulfert Hapke Christa Scheidt-Nave Anja Schienkiewitz Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany Health and Quality of Life Outcomes Metabolically healthy obesity SF-36 Physical component summary Sex Socio-economic status Lifestyle |
| author_facet |
Julia Truthmann Gert B. M. Mensink Anja Bosy-Westphal Ulfert Hapke Christa Scheidt-Nave Anja Schienkiewitz |
| author_sort |
Julia Truthmann |
| title |
Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany |
| title_short |
Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany |
| title_full |
Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany |
| title_fullStr |
Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany |
| title_full_unstemmed |
Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany |
| title_sort |
physical health-related quality of life in relation to metabolic health and obesity among men and women in germany |
| publisher |
BioMed Central |
| series |
Health and Quality of Life Outcomes |
| issn |
1477-7525 |
| publishDate |
2017-06-01 |
| description |
Abstract Background This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower HRQoL independent of metabolic health status and potential confounders, and (2) whether associations are similar in men and women. Methods We used cross-sectional data from the German Health Interview and Examination Survey 2008–11. Physical HRQoL was measured using the Short Form-36 version 2 physical component summary (PCS) score. Based on harmonized ATPIII criteria for the definition of the metabolic health and a body mass index ≥ 30 kg/m2 to define obesity, individuals were classified as metabolically healthy non-obese (MHNO), metabolically unhealthy non-obese (MUNO), metabolically healthy obese (MHO), and metabolically unhealthy obese (MUO). Sex-specific analyses including multivariable linear regression analyses were based on PCS as the dependent variable, metabolic health and obesity category as the independent variable with three categories and MHNO as the reference, and age, education, lifestyle and comorbidities as confounders. Results This study included 6860 participants (3298 men, 3562 women). Compared to MHNO, all other metabolic health and obesity categories had significantly lower PCS in both sexes. As reflected by the beta coefficients [95% confidence interval] from bivariable linear regression models, a significant inverse association with PCS was strongest for MUO (men: −7.0 [−8.2; −5.8]; women: −9.0 [−10.2; −7.9]), intermediate for MUNO (men: −4.2 [−5.3; −3.1]; women: −5.6 [−6.8; −4.4]) and least pronounced for MHO (men: −2.2 [−3.6; −0.8]; women −3.9 [−5.4; −2.5]). Differences in relation to MHNO remained statistically significant for all groups after adjusting for confounders, but decreased in particular for MUNO (men:–1.3 [−2.3; −0.3]; women: −1.5 [−2.7; −0.3]. Conclusions Obesity was significantly related to lower physical HRQoL, independent of metabolic health status. Potential confounders including age, educational status, health-related behaviors, and comorbidities explained parts of the inverse relationship. Associations were evident in both sexes and consistently more pronounced among women than men. |
| topic |
Metabolically healthy obesity SF-36 Physical component summary Sex Socio-economic status Lifestyle |
| url |
http://link.springer.com/article/10.1186/s12955-017-0688-7 |
| _version_ |
1612698442639867904 |