The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells

The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells

Abstract The Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway plays critical roles in orchestrating of immune system, especially cytokine receptors and they can modulate the polarization of T helper cells. This pathway is regulated by an array of regulator proteins,...

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Bibliographic Details
Main Authors: Farhad Seif, Majid Khoshmirsafa, Hossein Aazami, Monireh Mohsenzadegan, Gholamreza Sedighi, Mohammadali Bahar
Format: Article
Language:English
Published: BioMed Central 2017-06-01
Series:Cell Communication and Signaling
Online Access:http://link.springer.com/article/10.1186/s12964-017-0177-y

Internet

http://link.springer.com/article/10.1186/s12964-017-0177-y

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