Landscape reveals critical network structures for sharpening gene expression boundaries

Abstract Background Spatial pattern formation is a critical issue in developmental biology. Gene expression boundary sharpening has been observed from both experiments and modeling simulations. However, the mechanism to determine the sharpness of the boundary is not fully elucidated. Results We inve...

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Bibliographic Details
Main Authors: Chunhe Li, Lei Zhang, Qing Nie
Format: Article
Language:English
Published: BioMed Central 2018-06-01
Series:BMC Systems Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12918-018-0595-5