Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts

Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts

Abstract Galectin-9 (Gal9) has been postulated to have anti-inflammatory properties based on the ability of exogenous Gal9 to induce apoptosis in synovial fibroblasts in animal models of rheumatoid arthritis (RA). Here we aimed to assess the potential role of endogenous Galectins, including Gal9, in...

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Bibliographic Details
Main Authors: Mark J. Pearson, Magdalena A. Bik, Caroline Ospelt, Amy J. Naylor, Corinna Wehmeyer, Simon W. Jones, Christopher D. Buckley, Steffen Gay, Andrew Filer, Janet M. Lord
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:http://link.springer.com/article/10.1038/s41598-018-31173-3

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http://link.springer.com/article/10.1038/s41598-018-31173-3

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