Brain vascular heterogeneity: implications for disease pathogenesis and design of in vitro blood–brain barrier models

Brain vascular heterogeneity: implications for disease pathogenesis and design of in vitro blood–brain barrier models

Abstract The vertebrate blood–brain barrier (BBB) is composed of cerebral microvascular endothelial cells (CEC). The BBB acts as a semi-permeable cellular interface that tightly regulates bidirectional molecular transport between blood and the brain parenchyma in order to maintain cerebral homeostas...

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Bibliographic Details
Main Authors: Midrelle E. Noumbissi, Bianca Galasso, Monique F. Stins
Format: Article
Language:English
Published: BioMed Central 2018-04-01
Series:Fluids and Barriers of the CNS
Subjects:
Blood–brain barrier
Cerebral vasculature
Grey matter
In vitro models
Neurodegeneration
Neurovascular unit
Online Access:http://link.springer.com/article/10.1186/s12987-018-0097-2

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http://link.springer.com/article/10.1186/s12987-018-0097-2

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